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  Vol. 137 No. 6, June 2002 TABLE OF CONTENTS
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A Prospective, Randomized Trial of Laparoscopic Polytetrafluoroethylene (PTFE) Patch Repair vs Simple Cruroplasty for Large Hiatal Hernia

Constantine T. Frantzides, MD, PhD; Atul K. Madan, MD; Mark A. Carlson, MD; George P. Stavropoulos, MD

Arch Surg. 2002;137:649-652.

Hypothesis  Large hiatal hernias are prone to disruption, resulting in reherniation, when repaired with simple cruroplasty. The use of mesh may decrease the rate of reherniation in the laparoscopic repair of large hiatal hernias.

Design  Prospective, randomized controlled trial.

Setting  University-affiliated private hospital.

Patients  Seventy-two individuals undergoing laparoscopic Nissen fundoplication with a hernia defect greater or equal to 8 cm in diameter.

Intervention  Nissen fundoplication with posterior cruroplasty (n = 36) vs Nissen fundoplication with posterior cruroplasty and onlay of polytetrafluoroethylene (PTFE) mesh (n = 36).

Main Outcome Measures  Recurrences, complications, hospital stay, operative time, and cost.

Results  Patients in both groups had similar hospital stays, but the PTFE group had a longer operative time. The cost of the repair was $960 ± $70 more in the group with the prosthesis. Complications were minor and similar in both groups. There were 8 hernia recurrences (22%) in the primary repair group and none in the PTFE group (P<.006).

Conclusion  The use of prosthetic reinforcement of cruroplasty in large hiatal hernias may prevent hernia recurrences.


From the Departments of Surgery, Rush University, Chicago, Ill (Drs Frantzides, Madan, and Stavropoulos); and University of Nebraska Medical Center, Omaha (Dr Carlson).


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