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Arch Surg. 2006;141:1044.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Answer: Cecal Gastrointestinal Stromal Tumor

Gastrointestinal stromal tumor (GIST) is the designation for the specific c-kit–expressing and Kit signal–driven mesenchymal tumors. They account for approximately 0.1% to 3% of all gastrointestinal neoplasms and are the most common mesenchymal tumors that arise in the wall of the gastrointestinal tract.¹ Most individuals are older than 50 years at the time of presentation and rarely younger than 40 years. Primary colonic GISTs are much less common than gastric (60%-70%), small intestinal (25%-35%), and anorectal (<5%) and most commonly involve the muscularis propria of the intestinal wall with propensity for exophytic growth.² Therefore, the most common presentation is that of a mass arising from the intestinal wall and projecting into the abdominal cavity. Gastrointestinal stromal tumors can be histologically identified as highly cellular spindle cell or epithelioid mesenchymal tumors, and morphology is somewhat site dependent. However, common to all these tumors is expression of Kit (CD117 antigen), which is . . . [Full Text of this Article]

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Arch Surg. 2006;141(10):1043.
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