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  Vol. 141 No. 2, February 2006 TABLE OF CONTENTS
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Corticosteroid Use in the Intensive Care Unit: At What Cost?—Invited Critique

Michael F. Rotondo, MD; Paul J. Schenarts, MD

Arch Surg. 2006;141:149.

Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Machiavelli once said, "Anyone wishing to see what is to be must consider what has been."1 For nearly 40 years, enthusiasm for steroid use in the intensive care unit (ICU) has been like a pendulum, cyclically swinging toward and then away from their use. Currently, enthusiasm for steroid use appears to be on an upswing. Despite decades of conflicting data, steroids are once again being advocated for the treatment of sepsis. In addition, with a greater appreciation for the prevalence of "relative" adrenal insufficiency in the ICU, the use of steroids appears to be increasing. A historical review of the subject would lead one to proceed down this path with caution.

Britt and associates at Eastern Virginia Medical School have clearly articulated the results of a well-designed case-control study examining the complications associated with steroid use in the ICU. Their findings of . . . [Full Text of this Article]


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RELATED ARTICLE

Corticosteroid Use in the Intensive Care Unit: At What Cost?
Rebecca C. Britt, Alicia Devine, Karen C. Swallen, Leonard J. Weireter, Jay N. Collins, Frederic J. Cole, and L. D. Britt
Arch Surg. 2006;141(2):145-149.
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